Diaryloxyacetate herbicides

Pest Manag Sci. 2003 Jan;59(1):107-13. doi: 10.1002/ps.612.

Abstract

The discovery and investigation of a novel family of herbicides containing a diaryl acetal are described. The stability of the acetal limited herbicidal efficacy and recognizing that fact led to the design of analogs with commercial levels of post-emergence activity on broadleaf weeds. These compounds inhibited acetolactate synthase and in vitro activity data were used to guide target design. However, no members of this family provided a commercially valuable combination of herbicidal efficacy and crop selectivity.

MeSH terms

  • Acetolactate Synthase / antagonists & inhibitors
  • Acetolactate Synthase / metabolism
  • Herbicides / chemical synthesis*
  • Herbicides / chemistry
  • Herbicides / pharmacology*
  • Herbicides / toxicity
  • Molecular Structure
  • Plants / drug effects
  • Plants / enzymology
  • Structure-Activity Relationship

Substances

  • Herbicides
  • Acetolactate Synthase