Conducted a hemoperfusion (HP) experiment on AA-3 for the treatment of type III allergy in rabbits and observed the change of Cycle Immune Complex (CLC) and the blood mutual adaptation (BMA). The results showed that the CIC level was 195.52 +/- 12.79 ug/ml before adsorption and 119.01 +/- 10.4 micrograms/ml after ansorption, the adsorption rate being (39.13 +/- 2.19)%. The experiment also demonstrated satisfactory BMA during AA-3 HP.