[Positive photobiological investigation in Jessner's lymphocytic infiltration of the skin]

Ann Dermatol Venereol. 2002 Dec;129(12):1370-3.
[Article in French]

Abstract

Background: Jessner's lymphocytic infiltration of the skin is a rare and benign disorder. Its clinical course is cyclic with remissions and exacerbations. In this disease, photosensitivity was previously noticed by authors and recently demonstrated. We report four new cases with positive photobiological investigation.

Case reports: Four patients (2 males, 2 females), with a mean age 36 years were seen with erythematous papules or discoid plaques on face, arms and upper trunk. The onset of disease occurred after sun exposure in summer. Skin biopsies showed perivascular lymphocytic infiltration in the dermis. All patients relapsed cyclically with incomplete healing during winter. Photobiological investigation elicited skin lesions in a broad spectrum of UV: UVB (2 cases), UVA (1 case), UVA and UVB (1 case). In all patients treatment with oral antimalarials and external photoprotection was effective.

Discussion: Our data suggest that photosensitivity history in patients with Jessner's lymphocytic infiltration of the skin should be searched for, and confirmed by provocative phototesting. This relevant event could guide the therapeutic strategy because antimalarials were effective for the Jessner's lymphocytic infiltration cases with photosensitivity.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Antimalarials / therapeutic use
  • Female
  • Humans
  • Lymphocytes / pathology*
  • Male
  • Photosensitivity Disorders / etiology*
  • Skin Diseases / complications*
  • Skin Diseases / pathology*
  • Ultraviolet Rays / adverse effects

Substances

  • Antimalarials