[Genetic identification of the Crimean-Congo hemorrhagic fever virus during epidemic outbreak in Kazakhstan in 2000]

L N Iashina; V S Petrov; I D Petrova; V V Gutorov; S V Kazakov; K S Ospanov; S K Karimov; G I Tiunnikov; S V Seregin; I I Kuzina; I V Babkin; S V Netesov

[Genetic identification of the Crimean-Congo hemorrhagic fever virus during epidemic outbreak in Kazakhstan in 2000]

Mol Gen Mikrobiol Virusol. 2002:(4):31-5.

[Article in Russian]

Authors

L N Iashina¹, V S Petrov, I D Petrova, V V Gutorov, S V Kazakov, K S Ospanov, S K Karimov, G I Tiunnikov, S V Seregin, I I Kuzina, I V Babkin, S V Netesov

Affiliation

¹ State Research Center of Virology and Biotechnology Vector, Koltsovo, Novosibirsk Region, Russia.

PMID: 12534268

Abstract

Sera samples from patients suspected of Crimean-Congo hemorrhagic fever (CCHF) taken during epidemic outbreak at the territory of Sarysusky and Moiynkumsky districts of the Zhambyl region in Kazakhstan, in 2000, were analysed by means of reverse transcription-polymerase chain reaction (RT-PCR) and sequencing of virus genome fragments. Genome RNA of CCHF virus was found in 2 assays. Analysis of nucleotide sequences of fragments of S-segment of viral genome revealed in the Sarysusky districts circulation of CCHF virus, genetically resembled to close phylogenetically to CCHF virus strains from China.

Publication types

English Abstract

MeSH terms

Amino Acid Sequence
Amino Acid Substitution
China
Disease Outbreaks*
Genetic Variation
Hemorrhagic Fever Virus, Crimean-Congo / genetics*
Hemorrhagic Fever Virus, Crimean-Congo / isolation & purification
Hemorrhagic Fever, Crimean / epidemiology*
Hemorrhagic Fever, Crimean / virology*
Humans
Kazakhstan / epidemiology
Molecular Sequence Data
Phylogeny
Reverse Transcriptase Polymerase Chain Reaction
Sequence Analysis, DNA
Sequence Homology, Amino Acid