Abstract
This communication briefly summarizes the molecular characteristics, expression, electrophysiological and pharmacological properties of voltage-gated sodium channels in dorsal root ganglion (DRG) neurons, and the effects of voltage-gated sodium channels on regulation of nociceptive afferents.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Ganglia, Spinal / physiology*
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Humans
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Ion Channel Gating / physiology*
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NAV1.5 Voltage-Gated Sodium Channel
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Nociceptors / physiology*
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Sodium Channels / genetics
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Sodium Channels / physiology*
Substances
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NAV1.5 Voltage-Gated Sodium Channel
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SCN5A protein, human
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Sodium Channels