Abstract
Latency-associated transcripts of human herpesvirus 6 (H6LTs) (K. Kondo et al. J. Virol. 76:4145-4151, 2002) were maximally expressed at a fairly stable intermediate stage between latency and reactivation both in vivo and in vitro. H6LTs functioned as sources of immediate-early protein 1 at this stage, which up-regulated the viral reactivation.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Child
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Child, Preschool
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Hematopoietic Stem Cell Transplantation
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Herpesvirus 6, Human / genetics
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Herpesvirus 6, Human / physiology*
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Humans
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Immediate-Early Proteins / genetics
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Infant
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Open Reading Frames
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Phosphoproteins / genetics
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RNA, Messenger / analysis
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RNA, Viral / analysis
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Reverse Transcriptase Polymerase Chain Reaction
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Tetradecanoylphorbol Acetate / pharmacology
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Virus Latency*
Substances
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Immediate-Early Proteins
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Phosphoproteins
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RNA, Messenger
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RNA, Viral
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immediate-early 1 protein, human herpesvirus 6
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Tetradecanoylphorbol Acetate