Indolizidine and quinolizidine alkaloids

Nat Prod Rep. 2002 Dec;19(6):719-41. doi: 10.1039/b104969k.

Abstract

This review covers the isolation, structure determination, synthesis and biological activity of indolizidine and quinolizidine alkaloids from microbial, plant and animal sources. Included in the review are slaframine; hydroxylated indolizidines and their analogues; alkaloids from ants and amphibians; metabolites of the genera Prosopis, Streptomyces and Nuphar and the Lythraceae; phenanthroindolizidines and related alkaloids; lupin alkaloids; and alkaloids from sponges. tunicates and coccinellid beetles. The literature from July 2000 to June 2001 is reviewed, and 172 references are cited.

Publication types

  • Review

MeSH terms

  • Alkaloids* / chemical synthesis
  • Alkaloids* / chemistry
  • Alkaloids* / pharmacology
  • Amphibians
  • Animals
  • Ants / chemistry
  • Catalysis
  • Coleoptera / chemistry
  • Indolizines* / chemical synthesis
  • Indolizines* / chemistry
  • Indolizines* / pharmacology
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plants, Medicinal / chemistry
  • Porifera / chemistry
  • Quinolizines* / chemical synthesis
  • Quinolizines* / chemistry
  • Quinolizines* / pharmacology
  • Stereoisomerism
  • Streptomyces / chemistry
  • Streptomyces / metabolism
  • Urochordata / chemistry

Substances

  • Alkaloids
  • Indolizines
  • Quinolizines
  • slaframine