Trends in selenium biochemistry

Nat Prod Rep. 2002 Dec;19(6):693-718. doi: 10.1039/b205802m.

Abstract

The biochemistry of selenium-containing natural products, including selenoproteins, is reviewed up to May 2002. Particular emphasis is placed on the assimilation of selenium from inorganic and organic selenium sources for selenoprotein synthesis, the catalytic role of selenium in enzymes, and medical implications of an unbalanced selenium supply. The review contains 393 references on key discoveries and recent progress.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bacteria / chemistry
  • Base Sequence
  • Biochemical Phenomena
  • Biochemistry*
  • Biological Factors / chemistry*
  • Catalysis
  • Enzymes / chemistry*
  • Enzymes / metabolism*
  • Models, Molecular
  • Molecular Sequence Data
  • Molecular Structure
  • Plants / chemistry
  • Proteins / genetics
  • Proteins / metabolism
  • RNA, Transfer / chemistry
  • RNA, Transfer / genetics
  • Selenium* / chemistry
  • Selenium* / metabolism
  • Selenium* / pharmacology
  • Selenium* / physiology
  • Selenoproteins

Substances

  • Biological Factors
  • Enzymes
  • Proteins
  • Selenoproteins
  • RNA, Transfer
  • Selenium