[Distribution of bacteria and analysis of their sensibility to antibiotics in patients with hospital-acquired pneumonia]

Hunan Yi Ke Da Xue Xue Bao. 2000 Dec 28;25(6):567-9.
[Article in Chinese]

Abstract

Objectives: This study was explore the distribution of the bacteria and their sensibility to antibiotics in hospital-acquired pneumonia.

Methods: One hundred and ninety-six bacterium species were collected in patients with the hospital-acquired pneumonia to make sputum culture. The sensibility of the bacteria to antibiotics were examined by KB paper method and the minimal-inhibitory-concentration by gel double multiple dilute method.

Results: Most of the G- bacteria were pseudomonas aeruginosa (30%) and klebsiella bacillus (22%). Most of the G+ bacteria were staphylococcus epidermidis (14%) and staphylococcus aureus (12%). G- bacteria were sensitive to impienem(98%), cefoperazone(90%), ceftriaxone(90%), leftazidime(92%), ciprofloxacin(90%), and amikacin(89%). The sensibility of vancomycin to G+ bacteria was 100%.

Conclusions: The pseudomonas aeruginosa, klebsiella bacillus, staphylococcus epidermidis, and staphylococcus aureus are the most important bacteria in patients with hospital-acquired pneumonia. Imipenem, cefoperazone, ceftriazone, leftazidime, ciprofloxacin, amikacin, and vancomycin are effective antibiotics for treating hospital-acquired pneumonia.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cefoperazone / pharmacology
  • Ceftriaxone / pharmacology
  • Cross Infection / microbiology*
  • Female
  • Humans
  • Imipenem / pharmacology
  • Klebsiella Infections / microbiology
  • Klebsiella pneumoniae / drug effects
  • Male
  • Middle Aged
  • Pneumonia, Bacterial / microbiology*
  • Pseudomonas Infections / microbiology*
  • Pseudomonas aeruginosa / drug effects
  • Staphylococcal Infections / microbiology*
  • Staphylococcus epidermidis / drug effects

Substances

  • Imipenem
  • Ceftriaxone
  • Cefoperazone