Constituents of the fruits and leaves of Euodia daniellii

Arch Pharm Res. 2002 Dec;25(6):824-30. doi: 10.1007/BF02976999.

Abstract

Four flavonoid glycosides, flavaprin (7), evodioside B (8), vitexin (11), and hesperidin (12), as well as the coumarins bergapten (1), xanthotoxin (2), and isopimpinellin (3), the lignan simplexoside (10), the steroids beta-sitosterol (4) and daucosterol (5), the limonoids isolimonexic acid (6) and limonin (9), and uracil (13) and myo-inositol (14) have been isolated from Euodia daniellii. The structures of these compounds were established from spectral data. Among the isolates, bergapten showed cyclooxygenase-2 inhibitory activity with an IC50 value of 6.2 microg/ml. Flavonoids isolated from this plant exhibited no cytotoxic activity against the human tumor cell lines, A549, SKOV-3, SKMEL-2, XF498, and HCT15.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Evodia / chemistry*
  • Fruit / chemistry*
  • Humans
  • Plant Extracts / isolation & purification*
  • Plant Extracts / pharmacology*
  • Plant Leaves / chemistry*
  • Tumor Cells, Cultured / drug effects

Substances

  • Plant Extracts