Bilateral retinal hemorrhages in an 18-year-old woman

Surv Ophthalmol. 2002 Nov-Dec;47(6):590-3. doi: 10.1016/s0039-6257(02)00352-1.

Abstract

A previously healthy 18-year-old woman presented with sudden onset of central blurred vision in the right eye. Fundoscopic examination showed retinal venous tortuosity, several flame-shaped hemorrhages bilaterally, and a subhyaloid hemorrhage in the right fovea. Laboratory evaluation and subsequent bone marrow biopsy were consistent with the diagnosis of acute lymphoblastic leukemia. The retinal findings had cleared almost completely by three weeks after initiation of chemotherapy.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Daunorubicin / therapeutic use
  • Diagnosis, Differential
  • Female
  • Humans
  • Papilledema / etiology
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Prednisolone / therapeutic use
  • Retinal Hemorrhage / diagnosis*
  • Retinal Hemorrhage / drug therapy
  • Retinal Hemorrhage / etiology
  • Treatment Outcome
  • Vincristine / therapeutic use
  • Visual Acuity

Substances

  • Vincristine
  • Prednisolone
  • Daunorubicin

Supplementary concepts

  • DVP (daunomycin)