Abstract
Six new cadinene sesquiterpenoids, xenitorins A-F (1-6), were isolated from the methylene chloride solubles of the Formosan soft coral Xenia puerto-galerae. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Anthozoa / chemistry*
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / isolation & purification*
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Antineoplastic Agents / pharmacology
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Colonic Neoplasms
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Drug Screening Assays, Antitumor
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Humans
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Leukemia P388
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Lung Neoplasms
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Methylene Chloride
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Mice
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Molecular Conformation
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Sesquiterpenes / chemistry
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Sesquiterpenes / isolation & purification*
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Sesquiterpenes / pharmacology
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Spectrophotometry, Infrared
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Spectrophotometry, Ultraviolet
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Taiwan
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Tumor Cells, Cultured / drug effects
Substances
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Antineoplastic Agents
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Sesquiterpenes
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Methylene Chloride