A whitened face woman with nephrotic syndrome

Am J Kidney Dis. 2003 Jan;41(1):250-3. doi: 10.1053/ajkd.2003.50017.

Abstract

Skin whitening cream from developing countries is a recognized source of chronic mercury poisoning. The authors report on a 34-year-old Indonesian domestic helper who presented with nephrotic syndrome secondary to membranous nephropathy. It was subsequently found that she used a skin whitening cream regularly that was found to contain a mercury level of almost 2,000 times above the allowable limit. Her blood and urinary mercury levels were both grossly elevated. Her symptoms improved after she stopped using the cream. However, she returned to her home country before chelating therapy could be arranged. Because mercury-containing skin products are still widely available in developing countries, the use of these products should be considered a possible cause of membranous nephropathy in immigrants from those countries.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Ankle
  • Cosmetics / adverse effects
  • Cosmetics / chemistry
  • Cultural Characteristics*
  • Edema / blood
  • Edema / chemically induced
  • Edema / urine
  • Emigration and Immigration
  • Face*
  • Female
  • Glomerulonephritis, Membranous / blood
  • Glomerulonephritis, Membranous / chemically induced
  • Glomerulonephritis, Membranous / complications
  • Glomerulonephritis, Membranous / urine
  • Hong Kong / epidemiology
  • Humans
  • Mercury / blood
  • Mercury / urine
  • Mercury Poisoning / blood
  • Mercury Poisoning / complications
  • Mercury Poisoning / pathology
  • Mercury Poisoning / urine
  • Nephrotic Syndrome / blood
  • Nephrotic Syndrome / diagnosis*
  • Nephrotic Syndrome / etiology
  • Nephrotic Syndrome / urine

Substances

  • Cosmetics
  • Mercury