Abstract
From the hexane-soluble fraction of an ethanol extract from leaves and stems of Stemodia foliosa (Scrophulariaceae), the new stearic acid 4-[(n-pentoxy)phenethyl] ester (1) was isolated. This compound exhibited antibacterial properties at 10 microg/mL concentration by using disc diffusion method against Gram-positive bacteria Bacillus cereus and Bacillus subtilis and fast-acid bacterium Mycobacterium fortuitum. The structure of the new compound was elucidated by spectroscopic methods and by chemical conversion.
MeSH terms
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Anti-Bacterial Agents / pharmacology
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Bacteria / drug effects*
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Clarithromycin / pharmacology
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Magnetic Resonance Spectroscopy
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Molecular Structure
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Plant Extracts / pharmacology*
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Plant Leaves / chemistry
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Plant Stems / chemistry
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Scrophulariaceae*
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Stearates / chemistry
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Stearates / isolation & purification
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Stearates / pharmacology*
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Stearic Acids / chemistry
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Stearic Acids / pharmacology
Substances
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Anti-Bacterial Agents
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Plant Extracts
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Stearates
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Stearic Acids
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stearic acid 4-((n-pentoxy)phenethyl) ester
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stearic acid
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Clarithromycin