Preparation and investigation of antibacterial carbohydrate-based surfaces

Carbohydr Res. 2002 Nov 29;337(24):2495-9. doi: 10.1016/s0008-6215(02)00316-6.

Abstract

Surfaces bearing carbohydrate units have been modified in a two-step process to incorporate functionalities (lipophilic with polycationic units) that bear antibacterial activity. The effectiveness of these modified surfaces for antibacterial action against a series of seven Gram-positive and Gram-negative bacteria are reported.

MeSH terms

  • Anti-Infective Agents, Local / chemistry
  • Anti-Infective Agents, Local / pharmacology
  • Carbohydrates / chemistry
  • Carbohydrates / pharmacology*
  • Cotton Fiber
  • Detergents / chemical synthesis*
  • Detergents / chemistry
  • Detergents / pharmacology
  • Disinfectants / chemical synthesis*
  • Disinfectants / chemistry
  • Disinfectants / pharmacology
  • Gram-Negative Bacteria / drug effects
  • Gram-Negative Bacteria / growth & development
  • Gram-Positive Bacteria / drug effects
  • Gram-Positive Bacteria / growth & development
  • Quaternary Ammonium Compounds
  • Structure-Activity Relationship
  • Surface Properties

Substances

  • Anti-Infective Agents, Local
  • Carbohydrates
  • Detergents
  • Disinfectants
  • Quaternary Ammonium Compounds