The role of Mcl-1 and Bax expression alteration in the decreased rescue of human neutrophils from apoptosis by GM-CSF with aging

Ann N Y Acad Sci. 2002 Nov:973:305-8. doi: 10.1111/j.1749-6632.2002.tb04656.x.
No abstract available

MeSH terms

  • Aging / drug effects
  • Aging / physiology*
  • Apoptosis / drug effects
  • Apoptosis / physiology
  • Cellular Senescence / drug effects
  • Cellular Senescence / physiology*
  • Granulocyte-Macrophage Colony-Stimulating Factor / pharmacology*
  • Humans
  • Myeloid Cell Leukemia Sequence 1 Protein
  • Neoplasm Proteins / genetics*
  • Neutrophils / cytology
  • Neutrophils / drug effects
  • Neutrophils / physiology*
  • Proto-Oncogene Proteins / genetics*
  • Proto-Oncogene Proteins c-bcl-2*
  • bcl-2-Associated X Protein

Substances

  • BAX protein, human
  • Myeloid Cell Leukemia Sequence 1 Protein
  • Neoplasm Proteins
  • Proto-Oncogene Proteins
  • Proto-Oncogene Proteins c-bcl-2
  • bcl-2-Associated X Protein
  • Granulocyte-Macrophage Colony-Stimulating Factor