Seed-less iodine-125 ophthalmic applicator

Appl Radiat Isot. 2003 Jan;58(1):15-20. doi: 10.1016/s0969-8043(02)00236-1.

Abstract

A method of preparation a seed-less active insert of iodine-125 ophthalmic applicator is described. Internal electrolysis was applied for fixing iodine-125 on the concave surface of the silver shell which is afterwards hermetically sealed inside a spherically shaped acrylic insert. The current-voltage characteristics of the galvanic cell used for deposition of silver iodide were determined. The results of the measurements of the energy spectra of the radiation emitted by a seed-less and seed-containing applicator are presented. The iodine-125 surface distribution uniformity on a silver shell was measured. The depth dose rate measurements indicate that the total activity incorporated in a seed-less applicator can be lower than that in seed-containing, while simultaneously assuring the desired dose rate.

MeSH terms

  • Acrylates / chemistry
  • Brachytherapy / instrumentation*
  • Electrochemistry
  • Eye Neoplasms / radiotherapy
  • Humans
  • Iodine Radioisotopes / administration & dosage
  • Iodine Radioisotopes / chemistry
  • Iodine Radioisotopes / therapeutic use*
  • Ophthalmology / instrumentation*
  • Radiotherapy Dosage
  • Radiotherapy, High-Energy
  • Silver / chemistry

Substances

  • Acrylates
  • Iodine Radioisotopes
  • Silver