Study of the 111In-DTPA complex by the electromigration method

P I Ivanov; G D Bontchev; G A Bozhikov; D V Filossofov; O D Maslov; M V Milanov; S N Dmitriev

doi:10.1016/s0969-8043(02)00238-5

Study of the 111In-DTPA complex by the electromigration method

Appl Radiat Isot. 2003 Jan;58(1):1-4. doi: 10.1016/s0969-8043(02)00238-5.

Authors

P I Ivanov¹, G D Bontchev, G A Bozhikov, D V Filossofov, O D Maslov, M V Milanov, S N Dmitriev

Affiliation

¹ Flerov Laboratory of Nuclear Reaction, JINR, 141980 Dubna, Moscow region, Russian Federation. ivanov@lnr.jinr.ru

PMID: 12485655
DOI: 10.1016/s0969-8043(02)00238-5

Abstract

The electrophoretic behavior of the 111In-DTPA radiopharmaceutical has been investigated. The stability constant, diffusion coefficient and effective charge of the complex as well as the temperature dependence of the electrophoretic mobility were determined. No-carrier-added 111In with high specific activity was used in the electrophoretic experiments in ultramicroconcentrations (10(-9)M).

MeSH terms

Data Interpretation, Statistical
Diffusion
Drug Stability
Electrophoresis / methods
Hydrogen-Ion Concentration
Indium Radioisotopes / chemistry*
Osmolar Concentration
Pentetic Acid / analogs & derivatives*
Pentetic Acid / chemistry
Radiopharmaceuticals / chemistry*
Statistical Distributions
Temperature
Time Factors

Substances

Indium Radioisotopes
Radiopharmaceuticals
Pentetic Acid