It is observed increase in number of remedy intoxications in Lithuania, especially important is intoxication with psychotropic drugs and their mixtures. The thin-layer chromatography (TLC) method was proposed for separation and identification of drugs in mixture aminazine: nitrazepam: barbamylum. The mixture of these drugs excreted from body fluids (blood and urine) was investigated by TLC. Most acceptable these mobile phases: 1. Diethyl ether: dioxane--40:60. Rf values for drugs: aminazine 0.23-0.25; barbamylum 0.85-0.9; nitrazepam 0.75-0.8. 2. Diethyl ether: NH3 (25%): benzenum--80:10:10. Rf values for drugs: aminazine 0.55-0.58; barbamylum 0.32-0.35; nitrazepam 0.17-0.2.