Synthetic membrane transporters

Curr Opin Chem Biol. 2002 Dec;6(6):749-56. doi: 10.1016/s1367-5931(02)00399-x.

Abstract

An increasing number of synthetic compounds have been shown to facilitate ion and polar molecule transport across bilayer membranes. Most notably, recent advances in anion transport have yielded synthetic chloride channels and phospholipid translocases. Attention has also turned to the ability of short amino acid sequences to transport peptides and proteins across cellular membranes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Amino Acid Sequence
  • Anion Transport Proteins / chemistry*
  • Anion Transport Proteins / metabolism
  • Biological Transport
  • Carrier Proteins / chemistry
  • Carrier Proteins / metabolism
  • Cation Transport Proteins / chemistry*
  • Cation Transport Proteins / metabolism
  • Ion Channels / chemistry*
  • Ion Channels / metabolism
  • Lipid Bilayers / chemistry*
  • Lipid Bilayers / metabolism
  • Membrane Proteins / chemistry
  • Membrane Proteins / metabolism
  • Models, Molecular
  • Molecular Sequence Data
  • Peptides / chemistry*
  • Peptides / metabolism
  • Phospholipid Transfer Proteins*
  • Phospholipids / chemistry
  • Phospholipids / metabolism

Substances

  • Anion Transport Proteins
  • Carrier Proteins
  • Cation Transport Proteins
  • Ion Channels
  • Lipid Bilayers
  • Membrane Proteins
  • Peptides
  • Phospholipid Transfer Proteins
  • Phospholipids