Abstract
Over the past few years a number of new food ingredients labelled as being nutraceuticals have been launched on the food and pharmaceutical market. These include components that have a proven beneficial effect on human health, such as low-calorie sugars and B vitamins. Lactic acid bacteria, in particular Lactococcus lactis, have been demonstrated to be ideal cell factories for the production of these important nutraceuticals. Developments in the genetic engineering of food-grade microoganisms means that the production of certain nutraceuticals can be enhanced or newly induced through overexpression and/or disruption of relevant metabolic genes.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Antioxidants / metabolism
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Bacteria / classification
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Bacteria / metabolism
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Carbohydrate Metabolism*
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Folic Acid / biosynthesis
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Hexoses / biosynthesis
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Humans
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Intestines / microbiology*
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Lactococcus lactis / classification
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Lactococcus lactis / genetics*
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Lactococcus lactis / metabolism*
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Mannitol / metabolism
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Probiotics / administration & dosage
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Probiotics / metabolism*
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Riboflavin / biosynthesis
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Sorbitol / metabolism
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Species Specificity
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Trehalose / biosynthesis
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Vitamin B 12 / biosynthesis
Substances
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Antioxidants
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Hexoses
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Mannitol
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Sorbitol
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Folic Acid
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Trehalose
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Vitamin B 12
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tagatose
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Riboflavin