Mycoplasma hominis and Ureaplasma species brain abscess in a neonate

Pediatr Infect Dis J. 2002 Nov;21(11):1083-5. doi: 10.1097/00006454-200211000-00026.

Abstract

We report an infant with a mixed Mycoplasma and Ureaplasma brain abscess who was successfully treated with intravenous doxycycline and erythromycin. Therapeutic concentrations of doxycycline were demonstrated in cerebrospinal fluid. This report is evidence of the potential for Mycoplasma and Ureaplasma to produce focal central nervous system infection, as well as meningitis, in neonates and that use of doxycycline can be efficacious in the therapy of such infections.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Brain Abscess / complications
  • Brain Abscess / drug therapy
  • Brain Abscess / microbiology*
  • Doxycycline / therapeutic use
  • Humans
  • Infant, Newborn
  • Infant, Newborn, Diseases / drug therapy
  • Infant, Newborn, Diseases / microbiology*
  • Male
  • Mycoplasma Infections / complications*
  • Mycoplasma Infections / drug therapy
  • Mycoplasma Infections / microbiology
  • Mycoplasma hominis / isolation & purification*
  • Ureaplasma / isolation & purification*
  • Ureaplasma Infections / complications*
  • Ureaplasma Infections / drug therapy
  • Ureaplasma Infections / microbiology

Substances

  • Anti-Bacterial Agents
  • Doxycycline