[Interest in therapeutic drug monitoring of the main antibiotics]

S Davani; P Muret; B Royer; B Hoen; J-P Kantelip

[Interest in therapeutic drug monitoring of the main antibiotics]

Ann Biol Clin (Paris). 2002 Nov-Dec;60(6):655-61.

[Article in French]

Authors

S Davani¹, P Muret, B Royer, B Hoen, J-P Kantelip

Affiliation

¹ Laboratoire de pharmacologie, CHU Jean Minjoz, 25030 Besançon, France.

PMID: 12446229

Abstract

The therapeutic drug monitoring aims at optimising the prescribed dosages to improve efficacy and prevent toxicity. The aim of this study were to review the main pharmacodynamic and pharmacokinetic properties of aminoglycosides, glycopeptides and ceftazidime. Then, the therapeutic drug monitoring of these antibiotics and their methods of analysis is reviewed.

Publication types

English Abstract
Review

MeSH terms

Aminoglycosides
Anti-Bacterial Agents / blood
Anti-Bacterial Agents / pharmacokinetics*
Anti-Bacterial Agents / therapeutic use
Anti-Bacterial Agents / toxicity
Ceftazidime / pharmacokinetics
Drug Monitoring / methods
Humans
Teicoplanin
Vancomycin / pharmacokinetics

Substances

Aminoglycosides
Anti-Bacterial Agents
Teicoplanin
Vancomycin
Ceftazidime