Abstract
(+)-Lasonolide A was synthesized following the established procedure. (-)-Lasonolide A was found to be the biologically active enantiomer.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Antineoplastic Agents / chemical synthesis*
-
Antineoplastic Agents / chemistry
-
Cell Division / drug effects
-
Humans
-
Macrolides / chemical synthesis*
-
Macrolides / chemistry
-
Macrolides / pharmacology*
-
Optical Rotation
-
Stereoisomerism
-
Structure-Activity Relationship
-
Tumor Cells, Cultured
Substances
-
Antineoplastic Agents
-
Macrolides
-
lasonolide A