Synthesis of 1-(2-naphthylsulfonyl)pyrazole-C-glycosides

Nucleosides Nucleotides Nucleic Acids. 2002 Jun-Jul;21(6-7):469-75. doi: 10.1081/NCN-120014819.

Abstract

2-Naphthylsulfonylhydrazine was reacted with aromatic aldehydes or aldehydo sugars to give the corresponding hydrazones which undergo Michael addition reactions with malononitrile or ethyl cyanoacetate to form pyrazole derivatives.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetates / chemistry
  • Aldehydes
  • Glycosides / chemical synthesis*
  • Glycosides / chemistry
  • Hydrazines / chemistry
  • Magnetic Resonance Spectroscopy
  • Naphthalenesulfonates / chemistry*
  • Nitriles / chemistry
  • Pyrazoles / chemical synthesis*
  • Pyrazoles / chemistry

Substances

  • Acetates
  • Aldehydes
  • Glycosides
  • Hydrazines
  • Naphthalenesulfonates
  • Nitriles
  • Pyrazoles
  • hydrazine
  • dicyanmethane
  • ethyl cyanoacetate