Andirol A and B, two unique 6-hydroxymethylpterocarpenes from Andira inermis

Z Naturforsch C J Biosci. 2002 Sep-Oct;57(9-10):785-90. doi: 10.1515/znc-2002-9-1005.

Abstract

From a methanolic extract of the leaves of Andira inermis (Fabaceae), andirol A and B, two compounds with a novel type of a rotenoid-related skeleton and andinermol, a new 2-aryl-3-hydroxymethyl-benzofuran could be isolated. Characterisation and structure elucidation of these compounds was achieved on the basis of their spectral data. In addition, the in vitro activities of the isolated compounds against both the chloroquine-sensitive strain PoW and the chloroquine-resistant clone Dd2 of Plasmodium falciparum have been evaluated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry
  • Aldehydes / isolation & purification
  • Benzofurans / chemistry
  • Benzofurans / isolation & purification
  • Fabaceae / chemistry*
  • Heterocyclic Compounds, 4 or More Rings / chemistry*
  • Heterocyclic Compounds, 4 or More Rings / isolation & purification
  • Magnetic Resonance Spectroscopy
  • Methanol
  • Models, Molecular
  • Molecular Conformation
  • Plant Extracts / chemistry*
  • Plant Extracts / isolation & purification

Substances

  • Aldehydes
  • Benzofurans
  • Heterocyclic Compounds, 4 or More Rings
  • Plant Extracts
  • andinermal
  • andirol A
  • andirol B
  • Methanol