Participation of peripheral and spinal phosphodiesterases 4 and 5 in inflammatory pain

Proc West Pharmacol Soc. 2002:45:141-3.
No abstract available

MeSH terms

  • 3',5'-Cyclic-AMP Phosphodiesterases / physiology*
  • 3',5'-Cyclic-GMP Phosphodiesterases
  • Animals
  • Cyclic Nucleotide Phosphodiesterases, Type 4
  • Cyclic Nucleotide Phosphodiesterases, Type 5
  • Female
  • Formaldehyde
  • Inflammation / complications
  • Inflammation / drug therapy*
  • Inflammation / enzymology
  • Injections, Spinal
  • Pain / drug therapy*
  • Pain / enzymology
  • Pain / etiology
  • Pain Measurement / drug effects
  • Phosphodiesterase Inhibitors / administration & dosage
  • Phosphodiesterase Inhibitors / therapeutic use*
  • Phosphoric Diester Hydrolases / physiology*
  • Piperazines / administration & dosage
  • Piperazines / therapeutic use
  • Purines
  • Rats
  • Rats, Wistar
  • Rolipram / administration & dosage
  • Rolipram / therapeutic use
  • Sildenafil Citrate
  • Spinal Cord / enzymology*
  • Sulfones

Substances

  • Phosphodiesterase Inhibitors
  • Piperazines
  • Purines
  • Sulfones
  • Formaldehyde
  • Sildenafil Citrate
  • Phosphoric Diester Hydrolases
  • 3',5'-Cyclic-AMP Phosphodiesterases
  • Cyclic Nucleotide Phosphodiesterases, Type 4
  • 3',5'-Cyclic-GMP Phosphodiesterases
  • Cyclic Nucleotide Phosphodiesterases, Type 5
  • Pde5a protein, rat
  • Rolipram