Lung-specific expression of mutant p53 as mouse model for lung cancer

Methods Mol Med. 2003:74:465-80. doi: 10.1385/1-59259-323-2:465.

Authors

Kam-Meng Tchou-Wong¹, William N Rom

Affiliation

¹ Department of Medicine, Division of Pulmonary and Critical Care Medicine, NYU School of Medicine, New York, NY, USA.

PMID: 12415715
DOI: 10.1385/1-59259-323-2:465

No abstract available

MeSH terms

Adenocarcinoma / chemically induced
Adenocarcinoma / genetics*
Adenocarcinoma / pathology
Animals
Benzo(a)pyrene / toxicity
Carcinogens / toxicity
Disease Models, Animal*
Genes, p53 / genetics*
Humans
Injections, Intraperitoneal
Lung Neoplasms / chemically induced
Lung Neoplasms / genetics*
Lung Neoplasms / pathology
Mice
Mice, Transgenic / genetics*
Mutation*
Nitrosamines / toxicity
Proliferating Cell Nuclear Antigen / metabolism
Promoter Regions, Genetic
Proteins / metabolism
Proteins / pharmacology
Uteroglobin*

Substances

Carcinogens
Nitrosamines
Proliferating Cell Nuclear Antigen
Proteins
SCGB1A1 protein, human
Scgb1a1 protein, mouse
Benzo(a)pyrene
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
Uteroglobin