Results of complex investigation of 64 children with dento-maxillary deformations are presented. Anamnestic data of mothers and children were analyzed. Examinations by different specialists--pediatrician, orthopedician, nephrologist revealed latent and severe diseases and functional disorders of the gastrointestinal tract, central and autonomic nervous system, kidneys causing metabolic disorders particularly mineral metabolism disturbances. The authors suggest joining all the deformations in a group of "dismetabolic" ones and to develop methods of treatment in collaboration with different specialists.