Calix[4]- and calix[5]arene-based multicavity macrocycles

Anna Notti; Salvatore Occhipinti; Sebastiano Pappalardo; Melchiorre F Parisi; Ilenia Pisagatti; Andrew J P White; David J Williams

doi:10.1021/jo025735w

Calix[4]- and calix[5]arene-based multicavity macrocycles

J Org Chem. 2002 Oct 18;67(21):7569-72. doi: 10.1021/jo025735w.

Authors

Anna Notti¹, Salvatore Occhipinti, Sebastiano Pappalardo, Melchiorre F Parisi, Ilenia Pisagatti, Andrew J P White, David J Williams

Affiliation

¹ Dipartimento di Chimica Organica e Biologica, Università di Messina, Salita Sperone 31, I-98166 Messina, Italy.

PMID: 12376001
DOI: 10.1021/jo025735w

Abstract

Synthesis and single-crystal X-ray structures of mixed triple and double calixarenes 6 and 7, obtained from the base-catalyzed condensation of calix[5]arene 1 with cone pertosylated calix[4]arene 2, are reported. VT-NMR studies on 7 are consistent with a molecular motion arising from the anti-gauche conformational interconversion of its ethylene linkages.