Anatomopathological lesions of bladder endometriosis are heterogeneous

Fertil Steril. 2002 Oct;78(4):740-2. doi: 10.1016/s0015-0282(02)03321-6.

Abstract

Objective: To present the anatomopathological characteristics of deep bladder endometriosis.

Design: Descriptive anatomapathological study.

Setting: A university hospital department of gynecological surgery.

Patient(s): Eleven consecutive patients complaining of pelvic pain and painful urinary functional symptoms.

Intervention(s): Laparoscopic partial cystectomy.

Main outcome measure(s): Macroscopic and microscopic characteristics of deep bladder endometriosis lesions.

Result(s): Deep bladder endometriosis lesions were extremely heterogeneous, not only in any one patient but also from one patient to another. Bladder muscularis propria presented three aspects: [1] hyperplasia of the fibromuscular tissue (4/11); [2] simple dissociation of the smooth muscle fiber bundles with no veritable "disorganization" (4/11); [3] simple thickening of the interstitial collagen network, or sclerosis (3/11). A histological adenomyotic nodule aspect was only observed in one patient (9%).

Conclusion(s): Bladder endometriosis is an enigmatic disease. No hypothesis can be proposed as a single explanation for its pathogenesis.

MeSH terms

  • Endometriosis / pathology*
  • Endometriosis / surgery
  • Female
  • Humans
  • Hyperplasia
  • Urinary Bladder Diseases / pathology*
  • Urinary Bladder Diseases / surgery