Aerosol Sch 1000. An anticholinergic bronchodilator

Am Rev Respir Dis. 1975 Apr;111(4):419-22. doi: 10.1164/arrd.1975.111.4.419.

Abstract

Atropine is known to be an effective bonrchodilator. We studied the effectiveness of aerosol Sch 1000, a derivative of atropine, in relieving bronchoconstriction in asthma. A single dose of drug was effective within 5 min, and the effect had a duration of 4 hours. No side effects were noted. The major effect of the drug appeared to be in large airways.

Publication types

  • Clinical Trial

MeSH terms

  • Adolescent
  • Adult
  • Aerosols
  • Asthma / drug therapy
  • Asthma / physiopathology
  • Atropine Derivatives*
  • Bronchodilator Agents / therapeutic use*
  • Clinical Trials as Topic
  • Forced Expiratory Volume
  • Humans
  • Ipratropium / administration & dosage
  • Ipratropium / therapeutic use*
  • Isoproterenol / administration & dosage
  • Isoproterenol / therapeutic use
  • Maximal Midexpiratory Flow Rate
  • Placebos
  • Vital Capacity

Substances

  • Aerosols
  • Atropine Derivatives
  • Bronchodilator Agents
  • Placebos
  • Ipratropium
  • Isoproterenol