Solid-phase synthesis and biological evaluation of a pepticinnamin E library

Angew Chem Int Ed Engl. 2002 Oct 4;41(19):3616-20; 3516. doi: 10.1002/1521-3773(20021004)41:19<3616::AID-ANIE3616>3.0.CO;2-F.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkyl and Aryl Transferases / antagonists & inhibitors*
  • Alkyl and Aryl Transferases / chemistry
  • Alkyl and Aryl Transferases / metabolism
  • Animals
  • Antineoplastic Agents / chemical synthesis*
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology*
  • Apoptosis / drug effects
  • Binding Sites
  • Cell Line, Transformed
  • Dogs
  • Enzyme Inhibitors / chemical synthesis
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology
  • Models, Molecular
  • Molecular Structure
  • Oligopeptides / chemical synthesis*
  • Oligopeptides / chemistry
  • Oligopeptides / pharmacology*
  • Protein Conformation
  • Tumor Cells, Cultured

Substances

  • Antineoplastic Agents
  • Enzyme Inhibitors
  • Oligopeptides
  • pepticinnamin E
  • Alkyl and Aryl Transferases
  • p21(ras) farnesyl-protein transferase