Cardiac arrest related to coronary spasm in patients with variant angina: a three-case study

J Intern Med. 2002 Oct;252(4):368-76. doi: 10.1046/j.1365-2796.2002.01044.x.

Abstract

We present three patients with variant angina pectoris and episodes of cardiac arrest. All of them had typical clinical symptoms, ST-segment changes in electrocardiogram, and coronary artery spasm confirmed by arteriography. They were treated with high doses of calcium antagonists and nitrates. An automatic cardioverter-defibrillator was implanted in the patient who developed ventricular fibrillation despite therapy with calcium antagonists. In another patient a DDD pacemaker was implanted because of high-degree atrioventricular block.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Amiodarone / administration & dosage
  • Amiodarone / therapeutic use
  • Angina Pectoris, Variant / complications*
  • Angina Pectoris, Variant / diagnosis
  • Angina Pectoris, Variant / diagnostic imaging
  • Angina Pectoris, Variant / drug therapy
  • Anti-Arrhythmia Agents / administration & dosage
  • Anti-Arrhythmia Agents / therapeutic use
  • Aspirin / administration & dosage
  • Aspirin / therapeutic use
  • Calcium Channel Blockers / administration & dosage
  • Calcium Channel Blockers / therapeutic use
  • Cardiovascular Agents / administration & dosage
  • Cardiovascular Agents / therapeutic use
  • Coronary Angiography
  • Diltiazem / administration & dosage
  • Diltiazem / therapeutic use
  • Electrocardiography
  • Female
  • Follow-Up Studies
  • Heart Arrest / etiology*
  • Heart Arrest / therapy
  • Heart Block / diagnosis
  • Heart Block / etiology
  • Heart Block / therapy
  • Humans
  • Male
  • Middle Aged
  • Nitrates / administration & dosage
  • Nitrates / therapeutic use
  • Nitroglycerin / administration & dosage
  • Nitroglycerin / therapeutic use
  • Pacemaker, Artificial
  • Platelet Aggregation Inhibitors / administration & dosage
  • Platelet Aggregation Inhibitors / therapeutic use
  • Spasm / etiology
  • Time Factors
  • Vasodilator Agents / administration & dosage
  • Vasodilator Agents / therapeutic use
  • Ventricular Fibrillation / etiology
  • Ventricular Fibrillation / therapy

Substances

  • Anti-Arrhythmia Agents
  • Calcium Channel Blockers
  • Cardiovascular Agents
  • Nitrates
  • Platelet Aggregation Inhibitors
  • Vasodilator Agents
  • Diltiazem
  • Nitroglycerin
  • Amiodarone
  • Aspirin