A new secosterol from the Indonesian octocoral Pachyclavularia violacea

J Nat Prod. 2002 Sep;65(9):1357-9. doi: 10.1021/np010592e.

Abstract

A new secosterol (1), along with pachyclavulariaenone B (3), was isolated from Pachyclavularia violacea. The structures of these compounds were established on the basis of the NMR and MS experiments.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromatography, High Pressure Liquid
  • Cnidaria / chemistry*
  • Colonic Neoplasms
  • Drug Screening Assays, Antitumor
  • Humans
  • Indonesia
  • Leukemia P388
  • Lung Neoplasms
  • Mass Spectrometry
  • Melanoma
  • Mice
  • Molecular Conformation
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Secosteroids / chemistry
  • Secosteroids / isolation & purification*
  • Secosteroids / pharmacology
  • Stereoisomerism
  • Tumor Cells, Cultured / drug effects

Substances

  • 3,11-dihydroxy-5,6-epoxy-24-methyl-9,11-secocholestan-9-one
  • Secosteroids
  • pachyclavulariaenone B