Background: Occurrence of a gingival cyst in adults that exhibits the histopathologic hallmarks of an odontogenic keratocyst (OKC) is rare.
Methods: Two cases of primary soft tissue OKC in an adult female are described. Both presented as an asymptomatic small nodule on the buccal gingiva of the anterior mandible.
Results: After simple excision, no recurrence was observed.
Conclusions: All available data indicate that, irrespective of the nomenclature, peripheral OKC should be included under the histopathological spectrum of gingival cysts in the adult.