Objective: To study and compare the immunologic function and antioxidative effect of Tongcao(Tongtuomu) and Xiao-Tongcao(Ximashanjingjiehua, Xinanxiuqiu, Ditanghua) polysaccharides.
Method: Mice were abdominally administrated with four kinds of polysaccharides at dosages of 80 mg/kg and 40 mg/kg for 7-10 days.
Result: Four kinds of polysaccharides could increase the serum-lysozyme activity, phagocytic function of MPS and the serum hemolysin-antibody level in mice, inhibit the delayed hypersensitivity induced by DNCB in mice and raise the serum-catalase activity in mice.
Conclusion: Four kinds of Tongcao or Xiao-Tongcao polysaccharides have immunoregulative function and antioxidative effect. The results could enrich the contents of "A Study on Species-Sorting and Quality of Tongcao-Xiao-Tongcao Crude Drugs".