A total of 3022 sera from patients with suspected trichinosis and healthy individuals were studied by enzyme immunoassay using the commercial test systems of the Ye.I. Martsinovsky Institute of Medical Parasitology and Tropical Medicine (Moscow) and of the private joint stock company "Vector-Best" (Novosibirsk). The study indicated the trichinosis situation of strain in all subjects of the Russian Federation, including the Tyumen Region. The proportion of positive serological assays during diagnostic studies was 15.4%, that of seroepidemiological surveys was 3.3%. This poor situation associated with this entity is confirmed by group, "familial", and single cases of clinical trichinosis associated with ingestion of the meat of brown bears, badgers, and dogs and pork. The presence of natural trichinosis foci in the Tyumen Region is unquestionable, there is no evidence for formed synanthropic foci. An increase in the risk of trichinosis infection in the region is favoured by both socioeconomical and environmental epizootological prerequisites associated with the factors of technogenic and anthropic pressure on the ecosystem. Growing epidemic hazard of trichinosis foci requires that controlling and preventive measures shall be included into social development programmes for the districts and south of the Tyumen Region.