SJ-3366 Sam Jin Pharmaceutical

Curr Opin Investig Drugs. 2002 Aug;3(8):1146-8.

Abstract

Sam Jin is investigating SJ-3366, a non-nucleoside reverse transcriptase inhibitor (NNRTI), for the potential treatment of HIV infection [302450]. As well as acting as an NNRTI, SJ-3366 also interferes with HIV-1 entry via an intermediate target formed after virus-cell attachment [341146], [363900]. As of June 1998, Sam Jin had been awarded a patent for SJ-3366 in South Africa, with applications pending in 22 other countries [302450].

Publication types

  • Review

MeSH terms

  • HIV Infections / drug therapy*
  • HIV Reverse Transcriptase / metabolism*
  • Humans
  • Patents as Topic
  • Pyrimidinones / pharmacology
  • Pyrimidinones / therapeutic use*
  • Reverse Transcriptase Inhibitors / pharmacology
  • Reverse Transcriptase Inhibitors / therapeutic use*

Substances

  • Pyrimidinones
  • Reverse Transcriptase Inhibitors
  • SJ3366
  • HIV Reverse Transcriptase