Alpha2-HS glycoprotein: a protein in search of a function

Diabetes Metab Res Rev. 2002 Jul-Aug;18(4):311-4. doi: 10.1002/dmrr.315.

Abstract

In this issue (pp. 305-310) Jun Ren and Amy J. Davidoff author an article entitled 'Alpha2-HS glycoprotein, a putative inhibitor of tyrosine kinase, prevents glucose toxicity associated with cardiomyocyte dysfunction'. The protein responsible for this biological activity has recently come to the forefront of research on the biological activity of plasma proteins.

Publication types

  • Comment
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Blood Proteins / physiology*
  • Glucose / toxicity
  • Heart / drug effects
  • Heart / physiology
  • Heart / physiopathology
  • Humans
  • Phosphotyrosine / metabolism
  • Protein-Tyrosine Kinases / antagonists & inhibitors
  • Rats
  • alpha-2-HS-Glycoprotein

Substances

  • AHSG protein, human
  • Blood Proteins
  • alpha-2-HS-Glycoprotein
  • Phosphotyrosine
  • Protein-Tyrosine Kinases
  • Glucose