Abstract
In our Paediatric Clinic we observed a case of transient aplastic crisis caused by Parvovirus B19 in a child and his mother, both affected by spherocytic haemolytic anemia. Anti-Parvovirus IgM antibody titre and viral search by PCR were positive. Anemia was treated with transfusion of concentrated red blood cells. In case of a family onset of hyperacute anemia it is necessary to consider a bone marrow aplastic crisis of the red series, induced by Parvovirus B19, especially if there is notice of an ongoing outbreak of erythema infectiosum.
Publication types
-
Case Reports
-
English Abstract
MeSH terms
-
Adult
-
Antibodies, Viral / immunology
-
Female
-
Humans
-
Immunoglobulin M / immunology
-
Infant, Newborn
-
Male
-
Parvoviridae Infections / drug therapy
-
Parvoviridae Infections / immunology
-
Parvoviridae Infections / virology*
-
Parvovirus B19, Human / immunology
-
Parvovirus B19, Human / isolation & purification*
-
Polymerase Chain Reaction
-
Red-Cell Aplasia, Pure / genetics*
-
Red-Cell Aplasia, Pure / virology*
-
Spherocytosis, Hereditary / genetics*
Substances
-
Antibodies, Viral
-
Immunoglobulin M