UK-2A, B, C and D, novel antifungal antibiotics from Streptomyces sp. 517-02 VI (2). Structure-activity relationships of UK-2A

J Antibiot (Tokyo). 2002 Jun;55(6):607-10. doi: 10.7164/antibiotics.55.607.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antifungal Agents / chemistry
  • Antifungal Agents / pharmacology*
  • Coloring Agents / chemistry
  • Inhibitory Concentration 50
  • LLC-PK1 Cells
  • Lactones / pharmacology*
  • Mitochondria, Heart / drug effects
  • Mitochondria, Heart / metabolism
  • Oxazines*
  • Pyridines / pharmacology*
  • Streptomyces / chemistry
  • Streptomyces / metabolism*
  • Structure-Activity Relationship
  • Swine
  • Xanthenes*

Substances

  • Antifungal Agents
  • Coloring Agents
  • Lactones
  • Oxazines
  • Pyridines
  • UK 2A
  • Xanthenes
  • resazurin