Apoptosis. A cinderella caspase takes center stage

Science. 2002 Aug 23;297(5585):1290-1. doi: 10.1126/science.1076118.
No abstract available

Publication types

  • Comment

MeSH terms

  • Animals
  • Apoptosis*
  • Apoptotic Protease-Activating Factor 1
  • Caspase 2
  • Caspase 3
  • Caspase 9
  • Caspases / genetics
  • Caspases / metabolism*
  • Cell Line, Transformed
  • Cytochrome c Group / metabolism
  • Enzyme Activation
  • Humans
  • Mice
  • Mice, Knockout
  • Mitochondria / metabolism
  • Mitochondria / physiology*
  • Models, Biological
  • Permeability
  • Protein Transport
  • Proteins / metabolism
  • Proto-Oncogene Proteins / metabolism
  • Proto-Oncogene Proteins c-bcl-2 / metabolism
  • RNA, Small Interfering
  • RNA, Untranslated
  • Signal Transduction
  • Tumor Cells, Cultured
  • bcl-2-Associated X Protein

Substances

  • APAF1 protein, human
  • Apaf1 protein, mouse
  • Apoptotic Protease-Activating Factor 1
  • Cytochrome c Group
  • Proteins
  • Proto-Oncogene Proteins
  • Proto-Oncogene Proteins c-bcl-2
  • RNA, Small Interfering
  • RNA, Untranslated
  • bcl-2-Associated X Protein
  • CASP3 protein, human
  • CASP9 protein, human
  • Casp3 protein, mouse
  • Casp9 protein, mouse
  • Caspase 2
  • Caspase 3
  • Caspase 9
  • Caspases