[Progresses in mouse chromosome engineering]

Sheng Wu Gong Cheng Xue Bao. 2002 May;18(3):272-5.
[Article in Chinese]

Abstract

Mouse chromosome engineering, characterized by deletion and rearrangement of large fragment of chromosome, has been an important method for studying the function of mouse genome on a large scale. The latest progress in mouse chromosome engineering was introduced.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Chromosome Deletion
  • Chromosomes*
  • Genetic Engineering*
  • Integrases / genetics
  • Mice / genetics*
  • Mutation
  • Viral Proteins / genetics

Substances

  • Viral Proteins
  • Cre recombinase
  • Integrases