Enzyme-catalysed oxygenation and deoxygenation routes to chiral thiosulfinates

Derek R Boyd; Narain D Sharma; Martina A Kennedy; Steven D Shepherd; John F Malone; André Alves-Areias; Robert Holt; Stig G Allenmark; Malin A Lemurell; Howard Dalton; Heather Luckarift

doi:10.1039/b203139f

Enzyme-catalysed oxygenation and deoxygenation routes to chiral thiosulfinates

Chem Commun (Camb). 2002 Jul 21:(14):1452-3. doi: 10.1039/b203139f.

Authors

Derek R Boyd¹, Narain D Sharma, Martina A Kennedy, Steven D Shepherd, John F Malone, André Alves-Areias, Robert Holt, Stig G Allenmark, Malin A Lemurell, Howard Dalton, Heather Luckarift

Affiliation

¹ School of Chemistry, Queen's University of Belfast, Belfast, UK BT9 5AG.

PMID: 12189839
DOI: 10.1039/b203139f

Abstract

Enantioenriched thiosulfinates have been obtained by dioxygenase- and chloroperoxidase-catalysed oxidation of 1,2-disulfides and dimethyl sulfoxide reductase-catalysed deoxygenation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acinetobacter / enzymology
Catalysis
Chloride Peroxidase / chemistry
Citrobacter / enzymology
Dioxygenases
Enzymes / chemistry*
Indicators and Reagents
Multienzyme Complexes / chemistry
Oxidation-Reduction
Oxygen / chemistry*
Oxygenases / chemistry
Pseudomonas putida / enzymology
Stereoisomerism
Thiosulfonic Acids / chemistry*

Substances

Enzymes
Indicators and Reagents
Multienzyme Complexes
Thiosulfonic Acids
Chloride Peroxidase
Oxygenases
Dioxygenases
naphthalene dioxygenase
toluene dioxygenase
Oxygen