Successful treatment with low-dose weekly methotrexate in a case of undifferentiated spondyloarthropathy coexisting with cutaneous polyarteritis nodosa

Clin Rheumatol. 2002 Aug;21(4):304-5. doi: 10.1007/s100670200079.

Abstract

A case of a 56-year-old woman diagnosed with HLA-B27-positive undifferentiated spondyloarthropathy who developed cutaneous lesions consistent with cutaneous polyarteritis nodosa is presented. The rarity of this association and the dramatic response of both conditions to low-dose weekly methotrexate are emphasised.

Publication types

  • Case Reports

MeSH terms

  • Dose-Response Relationship, Drug
  • Female
  • HLA-B27 Antigen / immunology
  • Humans
  • Immunosuppressive Agents / administration & dosage
  • Immunosuppressive Agents / therapeutic use*
  • Methotrexate / administration & dosage
  • Methotrexate / therapeutic use*
  • Middle Aged
  • Polyarteritis Nodosa / complications
  • Polyarteritis Nodosa / drug therapy*
  • Skin Diseases / complications
  • Skin Diseases / drug therapy*
  • Spondylitis, Ankylosing / complications
  • Spondylitis, Ankylosing / drug therapy*
  • Spondylitis, Ankylosing / immunology
  • Treatment Outcome

Substances

  • HLA-B27 Antigen
  • Immunosuppressive Agents
  • Methotrexate