Abstract
A case of a 56-year-old woman diagnosed with HLA-B27-positive undifferentiated spondyloarthropathy who developed cutaneous lesions consistent with cutaneous polyarteritis nodosa is presented. The rarity of this association and the dramatic response of both conditions to low-dose weekly methotrexate are emphasised.
MeSH terms
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Dose-Response Relationship, Drug
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Female
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HLA-B27 Antigen / immunology
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Humans
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Immunosuppressive Agents / administration & dosage
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Immunosuppressive Agents / therapeutic use*
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Methotrexate / administration & dosage
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Methotrexate / therapeutic use*
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Middle Aged
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Polyarteritis Nodosa / complications
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Polyarteritis Nodosa / drug therapy*
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Skin Diseases / complications
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Skin Diseases / drug therapy*
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Spondylitis, Ankylosing / complications
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Spondylitis, Ankylosing / drug therapy*
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Spondylitis, Ankylosing / immunology
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Treatment Outcome
Substances
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HLA-B27 Antigen
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Immunosuppressive Agents
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Methotrexate