Boar semen controlled delivery system: analysis of batch seasonal variability

Int J Pharm. 2002 Aug 21;242(1-2):385-7. doi: 10.1016/s0378-5173(02)00222-3.

Abstract

A new encapsulation technology of swine semen is proposed to improve the quality of stored spermatozoa and to obtain the controlled release of viable cells, reducing the number of instrumental inseminations. This technology has been employed to produce barium alginate gel capsules in different seasons; an analysis of batch reproducibility was performed, and total capsule diameter, gel thickness and weight of capsules were determined as indices of batch properties. A seasonal variability was found but each batch was substantially homogeneous. The variability could be related to the biological variability of the semen employed as raw material as well as to the technological process.

MeSH terms

  • Animals
  • Drug Compounding
  • In Vitro Techniques
  • Insemination, Artificial / methods*
  • Male
  • Particle Size
  • Seasons
  • Semen / cytology*
  • Semen / physiology
  • Semen Preservation*
  • Spermatozoa / physiology
  • Swine