[Pneumonia due to Legionella pneumophila in an immunocompromised child]

Ned Tijdschr Geneeskd. 2002 Jul 27;146(30):1420-3.
[Article in Dutch]

Abstract

A one-year-and-seven-months-old boy was hospitalised because of fever, cough and general malaise. A diagnosed tonsillitis and pneumonia were treated with intravenous antibiotics. His clinical condition worsened despite antibiotic therapy. After immunologic investigations revealed both a cellular and a humoral immune disorder, a broncho-alveolar lavage was performed. The culture revealed Legionella pneumophila. Antibiotic treatment was then changed to erythromycin in combination with rifampicin, with a good response. Although rarely described in childhood, one should consider L. pneumophila as a possible pathogen in immunocompromised children presenting with pneumonia.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Anti-Infective Agents / therapeutic use
  • Antibiotics, Antitubercular / therapeutic use
  • Bronchoalveolar Lavage Fluid / microbiology
  • Drug Therapy, Combination / therapeutic use
  • Erythromycin / therapeutic use
  • Fluoroquinolones
  • Humans
  • Immunocompromised Host*
  • Infant
  • Legionella pneumophila / isolation & purification
  • Legionnaires' Disease / diagnosis*
  • Legionnaires' Disease / drug therapy
  • Male
  • Pneumonia, Bacterial / diagnosis*
  • Pneumonia, Bacterial / drug therapy
  • Rifampin / therapeutic use
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Anti-Infective Agents
  • Antibiotics, Antitubercular
  • Fluoroquinolones
  • Erythromycin
  • Rifampin