Clerodane diterpenoids from Ajuga bracteosa Wall

Nat Prod Lett. 2002 Aug;16(4):255-9. doi: 10.1080/10575630290020578.

Abstract

The whole plant of Ajuga bracteosa afforded five compounds including one new clerodane diterpenoid designated as Bracteonin-A (1) 6alpha-acetoxy, 15 (R&S)-methoxy, 18-(4'-hydroxy, 3'-beta-methyl, 3'-alpha-acetoxy, butyryloxy) neoclerodane. The other compounds identified were 14,15-dihydroajugapitin, 14-hydro-15-hydroxy ajugapitin, beta-sitosterol, and stigmasterol. The structural elucidation was carried out by spectroscopic techniques.

MeSH terms

  • Ajuga / chemistry*
  • Chromatography, Thin Layer
  • Diterpenes / chemistry
  • Diterpenes / isolation & purification*
  • Diterpenes / pharmacokinetics
  • Diterpenes / pharmacology
  • Diterpenes, Clerodane
  • India
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plants, Medicinal / chemistry*
  • Sitosterols / chemistry
  • Spectroscopy, Fourier Transform Infrared
  • Stereoisomerism
  • Stigmasterol / chemistry

Substances

  • Diterpenes
  • Diterpenes, Clerodane
  • Sitosterols
  • bracteonin-A
  • gamma-sitosterol
  • Stigmasterol