Liquid phase interfacing and miniaturization in matrix-assisted laser desorption/ionization mass spectrometry

Proteomics. 2002 Apr;2(4):360-72. doi: 10.1002/1615-9861(200204)2:4<360::AID-PROT360>3.0.CO;2-Y.

Abstract

Mass spectrometry is becoming the major analytical tool in biology research. This short review summarizes the state-of-the-art in the interface miniaturization and strategies for analysis of limited sample amounts by matrix assisted laser desorption/ionization mass spectrometry.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Electrophoresis, Gel, Two-Dimensional / methods
  • Humans
  • Hydrogen-Ion Concentration
  • Miniaturization*
  • Proteins / analysis*
  • Solutions / chemistry
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization* / instrumentation
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization* / methods

Substances

  • Proteins
  • Solutions